Hodgkin lymphoma in children and adolescents
Englund, Ljungman, et al.
In this project we performed a survey of patients with Hodgkin lymphoma in Sweden during 25 years, an immunohistochemistry analysis of the micro environment around the tumor cells related to clinical parameters, a comparison of treatments outcomes in children/ young adults in Sweden and Denmark, and an analysis of the health care use after treatment.
Soft tissue sarcoma in in children and adolescents
Ljungman et al.
Ljungman is the Swedish PI for an international soft tissue sarcoma study and collaborates in a number of different studies where different aspects of diagnostics, treatment and follow-up are evaluated for a large number of different soft tissue sarcomas often within the frame of RCTs.
Pediatric brain tumor models (PDX) and treatment focusing novel targets as a complement to standard treatment
Swartling (IGP), Giraud, et al.
In preclinical models with xenografts, i.e. PDX or cell-lines, mice with implanted brain tumors can be treated with chemo- and/or radiotherapy or other novel targeted treatment to later be evaluated with CT, PET, MRI etc. The goal is that this information together with clinical information, with among other things sequenced tumor material, will lead to suggestions for individualized treatment.