Supportive treatments for cancer in children and adolescents

Interventions for procedural pain in children and adolescents with cancer
Ljungman, Hedén, Kamsvåg Magnusson et al.
Pain is a major problem for children with cancer. Pain can be procedure-related, treatment-related (side-effects of treatments such as chemotherapy and radiotherapy), and cancer-related. In this project, we study procedure-related pain and different pharmacological and psychological interventions in RCTs.

Interventions for oral mucositis in children and adolescents with cancer
Ljungman, Kamsvåg Magnusson, Thorsell, Blacker, et al.
Oral mucositis is a painful condition with inflammation and ulceration of the mucous membranes in the mouth, caused by chemo- and radiotherapy and is particularly frequent in hematopoietic stem cell transplantation. Pain intensity varies, but the pain is often so severe that the patient is unable to eat solid food or even to consume liquids. In very severe cases the patient cannot talk, nor swallow saliva. Specific pharmacological and psychological interventions that may prevent or can reduce oral mucositis symptoms are evaluated in RCTs.

Vitamin D in children with cancer
Frisk, Jackmann, et al.
The aim of this project is to investigate prevalence, degree and consequences of vitamin D deficiency in children treated for cancer and to study if supplementation may reduce these consequences. Possible clinical consequences of vitamin D deficiency like infections and other reasons for hospital admissions between chemotherapy treatments will be studied, and which dose of vitamin D that is needed to reach normal levels will be investigated.

Clinical mini-factory for individualized medication based on 3-D printer technique and nanotechnology in severe diseases
Paulsson, Ljungman, Liminga, Strömme, Bergström, et al.
In the treatment of children with severe diseases the appropriate dosage forms to administer the correct dose in a safe way are often missing. We plan to develop a hospital based function which will be able to deliver quality assured, well documented oral dosage forms (capsules) for a variety of drugs for individual dosage in children and later on also to other patients in need of personally adapted dosage.

Prepared for radiotherapy – Interventional program to support children and youth
Engvall, Cederved, Ljungman et al.
The overall goal for the project is to reduce anxiety and fear, as well as to promote knowledge, understanding of radiotherapy and to provide age-appropriate strategies so that children, with support from their family, can undergo RT in a safe and secure way. Collaboration is established with the department of game design at UU. Children, youth, parents and personnel will be involved in the development of the intervention based on the experiences in a previous project.

Last modified: 2021-12-14